CORONARY HEART DISEASE AND AN INCIDENTAL PARATHYROID CARCINOMA

Coronary Heart Disease and an Incidental Parathyroid Carcinoma

A 71-year-old woman was admitted with angina pectoris.During hospitalization she developed a myocardial infarction (NSTEMI).Laboratory results revealed a mild elevated troponin and an elevated Hand Sinks calcium level (3.35 mmol/l).Subsequently, there was a decreased phosphate (0.36 mmol/l [normal 0.81-1.62 mmol/l]) as well as 16-fold elevated seru

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Genome sequences of human cytomegalovirus strain TB40/E variants propagated in fibroblasts and epithelial cells

Abstract The advent of whole genome sequencing has revealed that common laboratory strains of human cytomegalovirus (HCMV) have major genetic deficiencies resulting from serial passage in fibroblasts.In particular, tropism for epithelial and endothelial cells is lost due to mutations disrupting genes UL128, UL130, or UL131A, which encode subunits o

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Anticancer effect of the antirheumatic drug leflunomide on oral squamous cell carcinoma by the inhibition of tumor angiogenesis

Abstract Objectives Leflunomide (LEF) is a conventional synthetic disease-modifying antirheumatic drug and suppresses T-cell proliferation and activity by inhibiting pyrimidine synthesis using dihydroorotase dehydrogenase (DHODH); however, several studies have demonstrated that LEF possesses anticancer and antiangiogenic effects in some malignant t

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Asthma Exacerbation (Adult), Blended Simulation

Abstract Introduction The objective structured clinical examination (OSCE) with standardized patients is commonly accepted as a reliable assessment of clinical skills.Simulation allows learners the opportunity to experience conditions and perform procedures in a safe, standardized environment.This OSCE case incorporates both the standardized patien

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